作者
David Jiménez, Drahomir Aujesky, Lisa Moores, Vicente Gómez, José Luis Lobo, Fernando Uresandi, Remedios Otero, Manuel Monreal, Alfonso Muriel, Roger D Yusen, RIETE investigators
发表日期
2010/8/9
期刊
Archives of internal medicine
卷号
170
期号
15
页码范围
1383-1389
出版商
American Medical Association
简介
Background
The Pulmonary Embolism Severity Index (PESI) estimates the risk of 30-day mortality in patients with acute pulmonary embolism (PE). We constructed a simplified version of the PESI.
Methods
The study retrospectively developed a simplified PESI clinical prediction rule for estimating the risk of 30-day mortality in a derivation cohort of Spanish outpatients. Simplified and original PESI performances were compared in the derivation cohort. The simplified PESI underwent retrospective external validation in an independent multinational cohort (Registro Informatizado de la Enfermedad Tromboembólica [RIETE] cohort) of outpatients.
Results
In the derivation data set, univariate logistic regression of the original 11 PESI variables led to the removal of variables that did not reach statistical significance and subsequently produced the simplified PESI that contained the variables of age, cancer, chronic …
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D Jiménez, D Aujesky, L Moores, V Gómez, JL Lobo… - Archives of internal medicine, 2010
