作者
Marie Catherine Lee, Rajendra S Bhati, Edina E von Rottenthaler, Angela M Reagan, Sloan B Karver, Richard R Reich, Gwendolyn P Quinn
发表日期
2013/11/1
来源
The American Journal of Surgery
卷号
206
期号
5
页码范围
625-631
出版商
Elsevier
简介
Background
Premenopausal women represent approximately 35% of new breast cancer diagnoses. Diagnosis and treatment may lead to substantial disruption in quality of life (QOL).
Methods
Premenopausal patients (aged 18 to 50 years) treated for nonmetastatic breast cancer completed a mailed questionnaire. Multiple self-reported QOL measures and clinical data were collected. Cluster analysis and Cronbach's α were used to validate the survey. Analysis of variance was performed for specific interventions. Lower interference scores conveyed higher QOL.
Results
The response rate was 49.8%. Cronbach's α was 0.96. Immediate contralateral prophylactic mastectomy (CPM) carried the highest interference (mean, 3.3148) with sexuality compared with no CPM (mean, 2.85) or delayed CPM (P = .03). Breast conservation had the least interference with appearance (P < .01) and work and finances (P = .02 …
学术搜索中的文章
MC Lee, RS Bhati, EE von Rottenthaler, AM Reagan… - The American Journal of Surgery, 2013