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Background:Maternal intake of vitamin D in pregnancy is a potentially modifiable but understudied risk factor for the development of asthma in children.

Objective:We investigated whether maternal vitamin D intake in pregnancy is associated with decreased risks of wheezing symptoms in young children.

Design:Subjects were from a birth cohort recruited in utero with the primary objective of identifying associations between maternal diet during pregnancy and asthma and allergies in children. A random sample of 2000 healthy pregnant women was recruited while attending antenatal clinics at the Aberdeen Maternity Hospital, Scotland, at ≈12 wk gestation. Maternal vitamin D intake was ascertained from a food-frequency questionnaire completed at 32 wk of gestation. The main outcome measures were wheezing symptoms, spirometry, bronchodilator response, atopic sensitization, and exhaled nitric oxide at 5 y …