作者
Joonas Sirola, Toni Rikkonen, Marjo Tuppurainen, Jukka S Jurvelin, Esko Alhava, Heikki Kröger
发表日期
2008/8
期刊
Calcified Tissue International
卷号
83
页码范围
93-100
出版商
Springer-Verlag
简介
The aim of the present study was to investigate the ability of grip strength measurements to predict fracture risk in perimenopausal women according to bone mineral density (BMD). A random sample of 971 perimenopausal women from the Kuopio Osteoporosis Risk Factor and Prevention study cohort was measured with dual-energy X-ray absorptiometry (DXA) at the femoral neck and grip strength with a pneumatic squeeze dynamometer in 5-year intervals from baseline (1989–1991). Fractures during the 15-year follow-up were recorded based on self-reports and validated from medical records. In the total sample and in osteopenic or osteoporotic women (T score < −1, n = 284) grip strength was not significantly associated with fracture-free survival rate (P = nonsignificant in Cox regression). In women with normal baseline BMD (N-BMD, T score > −1, n = 687) the lowest grip strength quartile had a …
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