作者
Jilliana Monnier, L Tognetti, M Miyamoto, M Suppa, E Cinotti, M Fontaine, J Perez, C Orte Cano, O Yélamos, S Puig, Arnaud Dubois, P Rubegni, V Del Marmol, J Malvehy, JL Perrot
发表日期
2020/12
期刊
Journal of the European Academy of Dermatology and Venereology
卷号
34
期号
12
页码范围
2914-2921
简介
Background
Line‐field confocal optical coherence tomography (LC‐OCT) is a non‐invasive optical technique recently developed for skin examination in vivo. It provides real‐time, high‐resolution vertical images with an isotropic resolution of ~1 µm and a penetration depth of ~500 µm.
Objectives
Study goals were to qualitatively/quantitatively characterize healthy skin at different body sites using LC‐OCT.
Methods
The skin of young healthy volunteers was imaged with a handheld LC‐OCT imaging device. Seven body sites (back of the hand, forehead, cheek, nose, chest, forearm and back) were investigated. An independent qualitative [cutaneous structures' description; visibility of keratinocytes' nuclei and dermal–epidermal junction (DEJ)] and quantitative [stratum corneum (SC)/epidermal thicknesses; height of dermal papillae] assessment of the LC‐OCT images was performed.
Results
A total of 88 LC‐OCT …
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J Monnier, L Tognetti, M Miyamoto, M Suppa, E Cinotti… - Journal of the European Academy of Dermatology and …, 2020