作者
Giulio Illuminati, F Schneider, Cesare Greco, Enrico Mangieri, M Schiariti, Gaetano Tanzilli, F Barillà, V Paravati, G Pizzardi, F Calio, F Miraldi, F Macrina, M Totaro, E Greco, G Mazzesi, L Tritapepe, M Toscano, F Vietri, N Meyer, J-B Ricco
发表日期
2015/4/1
期刊
European Journal of Vascular and Endovascular Surgery
卷号
49
期号
4
页码范围
366-374
出版商
WB Saunders
简介
Objectives
To evaluate the potential benefit of systematic preoperative coronary-artery angiography followed by selective coronary-artery revascularization on the incidence of myocardial infarction (MI) in patients undergoing carotid endarterectomy (CEA) without a previous history of coronary artery disease (CAD).
Methods
We randomised 426 patients who were candidates for CEA, with no history of CAD, a normal electrocardiogram (ECG), and a normal cardiac ultrasound. In group A (n = 216) all patients underwent coronary angiography before CEA. In group B (n = 210) CEA was performed without coronary angiography. Patients were not blinded for relevant assessments during follow-up. Primary end-point was the occurrence of MI at 3.5 years. The secondary end-point was the overall survival rate. Median length of follow-up was 6.2 years.
Results
In group A, coronary angiography revealed significant coronary …
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