作者
Felipe Queiroga Sarmento Guerra, Juliana Moura Mendes, Janiere Pereira de Sousa, Maria FB Morais-Braga, Bernadete Helena Cavalcante Santos, Henrique Douglas Melo Coutinho, Edeltrudes de Oliveira Lima
发表日期
2012/12/1
期刊
Natural product research
卷号
26
期号
23
页码范围
2235-2238
出版商
Taylor & Francis Group
简介
The genus Acinetobacter has gained importance in recent years due to involvement in serious infections and antimicrobial resistance. Many plants have been evaluated not only for direct antimicrobial activity, but also as resistance modifying agents. The Essential oil of Citrus limon (EOCL) addition at 156.25 µgmL−1 (MIC/8) sub-inhibitory concentration in the growth medium led to MIC decrease for amikacin, imipenem and meropenem. The Essential oil of Cinnamomum zeylanicum (EOCZ) addition at 78.125 µg mL−1 (MIC/8) sub-inhibitory concentrations in the growth medium caused drastic MIC reduction of amikacin. Results of combining antibiotics and essential oils had shown us a synergistic effect with both essential oils/amikacin combinations. An additive effect was observed with the combinations of both essential oils and gentamicin. The results of this study suggest that essential oil of C. limon and C …
引用总数
2012201320142015201620172018201920202021202220232024263791127651786