作者
Fa-Hsuan Lin, Hsin-Ju Lee, Jyrki Ahveninen, Iiro P Jääskeläinen, Hsiang-Yu Yu, Cheng-Chia Lee, Chien-Chen Chou, Wen-Jui Kuo
发表日期
2021/4/15
期刊
Neuroimage
卷号
230
页码范围
117746
出版商
Academic Press
简介
Intracranial stereoelectroencephalography (sEEG) provides unsurpassed sensitivity and specificity for human neurophysiology. However, functional mapping of brain functions has been limited because the implantations have sparse coverage and differ greatly across individuals. Here, we developed a distributed, anatomically realistic sEEG source-modeling approach for within- and between-subject analyses. In addition to intracranial event-related potentials (iERP), we estimated the sources of high broadband gamma activity (HBBG), a putative correlate of local neural firing. Our novel approach accounted for a significant portion of the variance of the sEEG measurements in leave-one-out cross-validation. After logarithmic transformations, the sensitivity and signal-to-noise ratio were linearly inversely related to the minimal distance between the brain location and electrode contacts (slope≈−3.6). The signa-to …
引用总数
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