作者
Nicola Principi, Susanna Esposito, Paola Marchisio, Roberto Gasparini, Piero Crovari
发表日期
2003/10/1
期刊
The Pediatric infectious disease journal
卷号
22
期号
10
页码范围
S207-S210
出版商
LWW
简介
Background.
Recent studies indicate that influenza can be clinically important in otherwise healthy children. However, the interpretation of many studies is limited because of lack of laboratory confirmation of influenza-like illnesses. Therefore it is difficult to conclude whether the socioeconomic impact of influenza justifies vaccinating all children regardless of age or underlying chronic disorders.
Methods.
We prospectively collected data from 3771 children younger than 14 years of age presenting to emergency departments or primary care pediatricians with symptoms of respiratory tract infection during the influenza season of 2001 to 2002. Influenza infections were verified by virus culture or polymerase chain reaction. We additionally randomized 303 children age 6 months to 5 years to receive either influenza vaccine (n= 202) or no vaccination (n= 101) before the influenza season. The socioeconomic impact of …
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N Principi, S Esposito, P Marchisio, R Gasparini… - The Pediatric infectious disease journal, 2003