作者
Massimiliano Cantinotti, Aldo Clerico, Michele Murzi, Simona Vittorini, Michele Emdin
发表日期
2008/4/1
来源
Clinica Chimica Acta
卷号
390
期号
1-2
页码范围
12-22
出版商
Elsevier
简介
BACKGROUND
The aim of this review is to understand the clinical usefulness of Brain Natriuretic Peptide (BNP) and N-terminal pro-Brain Natriuretic Peptide (NT-proBNP) in pediatric cardiology.
METHODS
A computerized literature search on National Library of Medicine using the keywords “BNP assay” and “NT-proBNP assay” was performed. Then, we refined the analysis to include only the studies specifically designed to evaluate the clinical usefulness of BNP and NT-proBNP assays in patients with congenital heart disease.
RESULTS
BNP and NT-proBNP are useful marker for diagnosis of heart failure, for the assessment of clinical severity and for the follow-up of congenital and pediatric heart diseases. However, results from different studies are often partial and not always univocal. Moreover, reference intervals in pediatric population have not yet been extensively evaluated.
CONCLUSIONS
BNP and NT …
学术搜索中的文章
M Cantinotti, A Clerico, M Murzi, S Vittorini, M Emdin - Clinica Chimica Acta, 2008