作者
Ghasem Bordbar, Mohammad Bagher Miri, Mahmoud Omidi, Saeed Shoja, Malihe Akhavan
发表日期
2020
期刊
Gastroenterology Research and Practice
卷号
2020
期号
1
页码范围
8213082
出版商
Hindawi
简介
Background. The unresponsiveness to conventional pharmacological treatments and their side effects have led patients with irritable bowel syndrome (IBS) to use complementary and alternative medicine such as herbal remedies. Beside, Zataria multiflora Boiss (ZM), Trachyspermum ammi L. (TA), and Anethum graveolens L. (AG) are being used as an antiseptic, carminative, and antispasmodic in traditional medicine. This trial investigated the efficacy and safety of a combination of ZM, AG, and TA essential oils in the treatment of IBS. Method. The present study was a randomized double‐blind clinical trial with parallel groups in Iran. Patients in the control arm received three tablets of 10 mg hyoscine butylbromide daily for two weeks, and the intervention arm was daily treated with two 250 mg softgel capsules containing 180 mg of essential oils of ZM, AG, and TA for two weeks. Primary outcomes were the …
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G Bordbar, MB Miri, M Omidi, S Shoja, M Akhavan - Gastroenterology Research and Practice, 2020