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To evaluate the possible protective effects of virgin coconut oil on alcohol-induced oxidative stress and serum lipid values in rats.

This is an experimental animal study.

The animals were gavaged with 30% ethanol (7ml/kg body weight/day) while 6.67ml/kg body weight/day of virgin coconut oil (VCNO) was administered for 4 weeks using a cannulated syringe.

Animals treated with ethanol alone showed a significant elevation in the level of malondialdehyde (MDA) as measured by thiobarbituric acid reactive substances (TBARS), which lowered the antioxidant defence system such as reduced glutathione (GSH) and catalase activities when compared with the control. Sperm count, sperm motility and serum testosterone levels were also significantly reduced in this group. Levels of total cholesterol/HDL (TC/HDL) ratio increased significantly in the ethanol-only treated group …