作者
Ellen J Thompson, Dylan M Williams, Alex J Walker, Ruth E Mitchell, Claire L Niedzwiedz, Tiffany C Yang, Charlotte F Huggins, Alex SF Kwong, Richard J Silverwood, Giorgio Di Gessa, Ruth CE Bowyer, Kate Northstone, Bo Hou, Michael J Green, Brian Dodgeon, Katie J Doores, Emma L Duncan, Frances MK Williams, Andrew Steptoe, David J Porteous, Rosemary RC McEachan, Laurie Tomlinson, Ben Goldacre, Praveetha Patalay, George B Ploubidis, Srinivasa Vittal Katikireddi, Kate Tilling, Christopher T Rentsch, Nicholas J Timpson, Nishi Chaturvedi, Claire J Steves
发表日期
2022/6/28
期刊
Nature Communications
卷号
13
期号
1
页码范围
1-11
出版商
Nature Publishing Group
简介
The frequency of, and risk factors for, long COVID are unclear among community-based individuals with a history of COVID-19. To elucidate the burden and possible causes of long COVID in the community, we coordinated analyses of survey data from 6907 individuals with self-reported COVID-19 from 10 UK longitudinal study (LS) samples and 1.1 million individuals with COVID-19 diagnostic codes in electronic healthcare records (EHR) collected by spring 2021. Proportions of presumed COVID-19 cases in LS reporting any symptoms for 12+ weeks ranged from 7.8% and 17% (with 1.2 to 4.8% reporting debilitating symptoms). Increasing age, female sex, white ethnicity, poor pre-pandemic general and mental health, overweight/obesity, and asthma were associated with prolonged symptoms in both LS and EHR data, but findings for other factors, such as cardio-metabolic parameters, were inconclusive.
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