作者
Krishnan Bhaskaran, Sebastian Bacon, Stephen JW Evans, Chris J Bates, Christopher T Rentsch, Brian MacKenna, Laurie Tomlinson, Alex J Walker, Anna Schultze, Caroline E Morton, Daniel Grint, Amir Mehrkar, Rosalind M Eggo, Peter Inglesby, Ian J Douglas, Helen I McDonald, Jonathan Cockburn, Elizabeth J Williamson, David Evans, Helen J Curtis, William J Hulme, John Parry, Frank Hester, Sam Harper, David Spiegelhalter, Liam Smeeth, Ben Goldacre
发表日期
2021/7/1
期刊
The Lancet Regional Health–Europe
卷号
6
出版商
Elsevier
简介
Background
Mortality from COVID-19 shows a strong relationship with age and pre-existing medical conditions, as does mortality from other causes. We aimed to investigate how specific factors are differentially associated with COVID-19 mortality as compared to mortality from causes other than COVID-19.
Methods
Working on behalf of NHS England, we carried out a cohort study within the OpenSAFELY platform. Primary care data from England were linked to national death registrations. We included all adults (aged ≥18 years) in the database on 1st February 2020 and with >1 year of continuous prior registration; the cut-off date for deaths was 9th November 2020. Associations between individual-level characteristics and COVID-19 and non-COVID deaths, classified according to the presence of a COVID-19 code as the underlying cause of death on the death certificate, were estimated by fitting age- and sex …
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K Bhaskaran, S Bacon, SJW Evans, CJ Bates… - The Lancet Regional Health–Europe, 2021