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The most common etiologic cause of thyrotoxicosis in children and adults is autoimmune Graves’(Basedow’s) disease. Anti thyroid medications, surgery and radioactive iodine have been used in the treatment of Graves’ hyperthyroidism for more than six decades. The use of antithyroid drugs is the most common therapeutic approach. However, long-term remission with antithyroid drugs can be expected in 20–50% of adults and 20–30% of children. The methods for definitive