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Adolescent obesity is difficult to assess in multi‐ethnic populations using BMI, due to variability in the BMI–fatness relationship. We aimed to describe body composition (BC), and to validate leg–leg bioelectrical impedance analysis (BIA), in adolescents from different ethnic groups using deuterium (D₂O) as the reference method. Measurements were made of weight, height, total body water (TBW), and BIA (TANITA TBF‐300) in 110 white, 170 Asian, and 102 black adolescents aged 11–15 years. TBW was converted to lean mass (LM) using assumed hydration of lean tissue. General linear models were used to compare BC by D₂O between the ethnic groups. BC values from D₂O were compared with TANITA values, and used to generate ethnic‐specific prediction equations in the whole sample, and also in equation‐generation (group 1) and cross‐validation (group 2) subsamples. Ethnic variability in BMI did not …