作者
Guido Serini, Giulio Gabbiani
发表日期
1999/8/1
来源
Experimental cell research
卷号
250
期号
2
页码范围
273-283
出版商
Academic Press
简介
The name myofibroblast was proposed several years ago for fibroblastic cells located within granulation tissue and exhibiting an important cytoplasmic microfilamentous apparatus [1, 2]. The suggestion that these cells are responsible for the phenomenon of wound contraction was rapidly taken into consideration because about the same time the concept that any cell, and not only muscle cells, is provided with a contractile apparatus responsible for the regulation of such phenomena as cell shape modulation or cell motility was becoming more and more popular (for review see [3]). Several laboratories have reported the presence of cells with myofibroblastic features during a variety of pathological situations [3] and also in normal tissues, where they could exert a mechanical function (for review see [4]). Table 1 lists the locations of myofibroblasts in normal tissues. Later, it was observed that the microfilamentous …
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