作者
Mark S Graham, Anna May, Thomas Varsavsky, Carole H Sudre, Benjamin Murray, Kerstin Kläser, Michela Antonelli, Liane S Canas, Erika Molteni, Marc Modat, M Jorge Cardoso, David A Drew, Long H Nguyen, Benjamin Rader, Christina Hu, Joan Capdevila, Alexander Hammers, Andrew T Chan, Jonathan Wolf, John S Brownstein, Tim D Spector, Sebastien Ourselin, Claire J Steves, Christina M Astley
发表日期
2021/3/17
期刊
MedRxiv
页码范围
2021.03. 16.21253719
出版商
Cold Spring Harbor Laboratory Press
简介
Background
Symptomatic testing programmes are crucial to the COVID-19 pandemic response. We sought to examine United Kingdom (UK) testing rates amongst individuals with test-qualifying symptoms, and factors associated with not testing.
Methods
We analysed a cohort of untested symptomatic app users (N=1,237), nested in the Zoe COVID Symptom Study (Zoe, N= 4,394,948); and symptomatic survey respondents who wanted, but did not have a test (N=1,956), drawn from the University of Maryland-Facebook Covid-19 Symptom Survey (UMD-Facebook, N=775,746).
Findings
The proportion tested among individuals with incident test-qualifying symptoms rose from ∼20% to ∼75% from April to December 2020 in Zoe. Testing was lower with one vs more symptoms (73.0% vs 85.0%), or short vs long symptom duration (72.6% vs 87.8%). 40.4% of survey respondents did not identify all three test-qualifying symptoms. Symptom identification decreased for every decade older (OR=0.908 [95% CI 0.883-0.933]). Amongst symptomatic UMD-Facebook respondents who wanted but did not have a test, not knowing where to go was the most cited factor (32.4%); this increased for each decade older (OR=1.207 [1.129-1.292]) and for every 4-years fewer in education (OR=0.685 [0.599-0.783]).
Interpretation
Despite current UK messaging on COVID-19 testing, there is a knowledge gap about when and where to test, and this may be contributing to the ∼25% testing gap. Risk factors, including older age and less education, highlight potential opportunities to tailor public health messages.
Funding
Zoe Global Limited, Department of Health, Wellcome Trust …
引用总数
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