作者
Stephen M Cohn, Avery B Nathens, Frederick A Moore, Peter Rhee, Juan Carlos Puyana, Ernest E Moore, Gregory J Beilman, StO2 in Trauma Patients Trial Investigators
发表日期
2007/1/1
期刊
Journal of Trauma and Acute Care Surgery
卷号
62
期号
1
页码范围
44-55
出版商
LWW
简介
Background:
Near-infrared spectroscopy (NIRS) can continuously and noninvasively monitor tissue oxygen saturation (StO 2) in muscle and may be an indicator of shock severity. Our purpose was to evaluate how well StO 2 predicted outcome in high-risk torso trauma patients presenting in shock.
Methods:
The primary outcome in this prospective study was multiple organ dysfunction syndrome (MODS). StO 2 data were obtained upon hospital arrival and for 24 hours along with other known predictors of hypoperfusion and clinical outcomes. Clinicians were blinded to StO 2 measurements.
Results:
Seven Level I trauma centers enrolled 383 patients, 50 of whom developed MODS. Minimum StO 2 performed similarly to maximum base deficit (BD) in discrimination of MODS patients. The sensitivity for both measures (StO 2 cutoff= 75%; BD cutoff= 6 mEq/L) was 78%, the specificity was 34% to 39%, the positive predictive …
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