作者
James F Sanchez, Amber D Somoza, Nancy P Keller, Clay CC Wang
发表日期
2012/2/14
来源
Natural product reports
卷号
29
期号
3
页码范围
351-371
出版商
The Royal Society of Chemistry
简介
Covering: 2005 to 2011 This review studies the impact of whole genome sequencing on Aspergillus secondary metabolite research. There has been a proliferation of many new, intriguing discoveries since sequencing data became widely available. What is more, the genomes disclosed the surprising finding that there are many more secondary metabolite biosynthetic pathways than laboratory research had suggested. Activating these pathways has been met with some success, but many more dormant genes remain to be awakened.
学术搜索中的文章
JF Sanchez, AD Somoza, NP Keller, CCC Wang - Natural product reports, 2012