作者
Edson Bor-Seng-Shu, Ricardo De Carvalho Nogueira, Eberval G Figueiredo, Eli Faria Evaristo, Adriana Bastos Conforto, Manoel Jacobsen Teixeira
发表日期
2012/1/1
来源
Neurosurgical Focus
卷号
32
期号
1
页码范围
E5
出版商
American Association of Neurological Surgeons
简介
Object
Sonothrombolysis has recently been considered an emerging modality for the treatment of stroke. The purpose of the present paper was to review randomized clinical studies concerning the effects of sonothrombolysis associated with tissue plasminogen activator (tPA) on acute ischemic stroke.
Methods
Systematic searches for literature published between January 1996 and July 2011 were performed for studies regarding sonothrombolysis combined with tPA for acute ischemic stroke. Only randomized controlled trials were included. Data extraction was based on ultrasound variables, patient characteristics, and outcome variables (rate of intracranial hemorrhages and arterial recanalization).
Results
Four trials were included in this study; 2 trials evaluated the effect of transcranial Doppler (TCD) ultrasonography on sonothrombolysis, and 2 …
学术搜索中的文章
E Bor-Seng-Shu, RDC Nogueira, EG Figueiredo… - Neurosurgical Focus, 2012