作者
Peter Peng, Omar Hyder, Amin Firoozmand, Peter Kneuertz, Richard D Schulick, Donghang Huang, Martin Makary, Kenzo Hirose, Barish Edil, Michael A Choti, Joseph Herman, John L Cameron, Christopher L Wolfgang, Timothy M Pawlik
发表日期
2012/8/1
期刊
Journal of gastrointestinal surgery
卷号
16
期号
8
页码范围
1478-1486
出版商
No longer published by Elsevier
简介
Introduction
Assessing patient-specific risk factors for long-term mortality following resection of pancreatic adenocarcinoma can be difficult. Sarcopenia—the measurement of muscle wasting—may be a more objective and comprehensive patient-specific factor associated with long-term survival.
Methods
Total psoas area (TPA) was measured on preoperative cross-sectional imaging in 557 patients undergoing resection of pancreatic adenocarcinoma between 1996 and 2010. Sarcopenia was defined as the presence of a TPA in the lowest sex-specific quartile. The impact of sarcopenia on 90-day, 1-year, and 3-year mortality was assessed relative to other clinicopathological factors.
Results
Mean patient age was 65.7 years and 53.1 % was male. Mean TPA among men (611 mm2/m2) was greater than among women (454 mm2/m2). Surgery involved pancreaticoduodenectomy (86.0 %) or distal pancreatectomy (14.0 …
学术搜索中的文章
P Peng, O Hyder, A Firoozmand, P Kneuertz… - Journal of gastrointestinal surgery, 2012