作者
Jessica R Furst, Leonardo C Bandeira, Wen-Wei Fan, Sanchita Agarwal, Kyle K Nishiyama, Donald J McMahon, Elzbieta Dworakowski, Hongfeng Jiang, Shonni J Silverberg, Mishaela R Rubin
发表日期
2016/6/1
期刊
The Journal of Clinical Endocrinology & Metabolism
卷号
101
期号
6
页码范围
2502-2510
出版商
Oxford University Press
简介
Context
Skeletal deterioration, leading to an increased risk of fracture, is a known complication of type 2 diabetes mellitus (T2D). Yet plausible mechanisms to account for skeletal fragility in T2D have not been clearly established.
Objective
The objective of the study was to determine whether bone material properties, as measured by reference point indentation, and advanced glycation endproducts (AGEs), as determined by skin autofluorescence (SAF), are related in patients with T2D.
Design
This was a cross-sectional study.
Setting
The study was conducted at a tertiary medical center.
Patients
Sixteen postmenopausal women with T2D and 19 matched controls participated in the study.
Main Outcome Measures
Bone material strength index (BMSi) by in vivo reference point indentation, AGE …
引用总数
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学术搜索中的文章
JR Furst, LC Bandeira, WW Fan, S Agarwal… - The Journal of Clinical Endocrinology & Metabolism, 2016