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The objective of this work to study the effect of six plant extracts, Ocimum basilicum (Sweat Basil), Azadirachta indica (Neem), Eucalyptus chamadulonsis (Eucalyptus), Datura stramonium (Jimsonweed), Nerium oleander (Oleander) and Allium sativum (Garlic) against Alternaria solani in vitro and in vivo. In in vitro study the leaf extracts of D. stramonium, A. indica and A. sativum at 5% concentration caused highest reduction of mycelial growth of A. solani (44.4, 43.3 and 42.2%, respectively), while O. basilicum at 1 and 5% and N. oleander at 5% caused the lowest inhibition of mycelia growth of the pathogen. In greenhouse experiments the highest reduction of disease severity was achieved by fungicide (Ridomil Plus 50% WP, 15% metalaxy+35% Copper oxychloride, at 2 g L^-1) 82.8% followed by the extracts of A. sativum at 5% and D. stramonium at 1 and 5% concentration. The greatest reduction of disease …