作者
Francesco De Francesco, Antonio Graziano, Letizia Trovato, Gabriele Ceccarelli, Maurizio Romano, Marco Marcarelli, Gabriella Maria Cusella De Angelis, Umberto Cillo, Michele Riccio, Giuseppe Andrea Ferraro
发表日期
2017/2
来源
Stem Cell Reviews and Reports
卷号
13
页码范围
139-148
出版商
Springer US
简介
Background
The etiology of non-healing ulcers depends on both systemic and local factors. The introduction of advanced dressing, negative wound therapy and compression therapy have undoubtedly improved clinical outcomes. The principal aim of study was to demonstrate the efficacy of dermal micrografts in the treatment of ulcers with different etiologies. The second aim was to investigate in vitro the action of micrografts in the regenerative process.
Methods
The dermal micro-grafts were obtained from mechanical disaggregation of small pieces of skin tissue through a medical device called Rigeneracons.
Results
We observed in vivo the ability of dermal autologous micrografts to improve the healing of venous, diabetic, pressure and post-traumatic ulcers after few week of treatment accomplished in general with a …
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F De Francesco, A Graziano, L Trovato, G Ceccarelli… - Stem Cell Reviews and Reports, 2017