作者
Atul Dev, Soni Jignesh Mohanbhai, Avinash Chandra Kushwaha, Ankur Sood, Mohammed Nadim Sardoiwala, Subhasree Roy Choudhury, Surajit Karmakar
发表日期
2020/6/1
期刊
Acta Biomaterialia
卷号
109
页码范围
121-131
出版商
Elsevier
简介
Wound healing remains a healthcare challenge in patients suffering from grave tissue damage due to burn injuries and severe medical conditions like diabetes and ischemia. A repeated wound dressing in such cases leads to tissue damage, which could further inflate the wound healing. It is also challenging to analyze the depth of wound bed in these conditions, which could affect the recovery period. To address this need, we have developed an injectable hydrogel from natural polysaccharide κ-carrageenan and a pigmented protein C-phycocyanin. C-phycocyanin has wound healing, antimicrobial, antioxidant and anti-inflammatory properties along with the In-vivo fluorescence imaging ability. Gelling property of κ-carrageenan could be utilized along with C-phycocyanin as an injectable and regenerative wound dressings matrix to monitor wound healing in real-time without upsetting the healing process. The …
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