作者
Pasquale Martinelli, Riccardo Troncone, F Paparo, P Torre, Emilia Trapanese, C Fasano, A Lamberti, Gabriele Budillon, G Nardone, Luigi Greco
发表日期
2000/3/1
期刊
Gut
卷号
46
期号
3
页码范围
332-335
出版商
BMJ Publishing Group
简介
BACKGROUND
Up to 50% of women with untreated coeliac disease experience miscarriage or an unfavourable outcome of pregnancy. In most cases, after 6–12 months of a gluten free diet, no excess of unfavourable outcome of pregnancy is observed. The prevalence of undiagnosed coeliac disease among pregnant women is not known.
AIM
To determine the prevalence of untreated coeliac disease among women attending the obstetrics-gynaecological department.
METHODS
Endomysial antibodies, which are specific and sensitive for coeliac disease, were evaluated in all women attending the obstetrics-gynaecology department of a large city hospital over a 90 day period.
RESULTS
Of 845 pregnant women screened, 12 were identified as having coeliac disease. Three had previously been diagnosed but were not following a gluten free diet. The remaining nine underwent a small intestinal biopsy, which …
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