作者
Abdullah F Al Harthi, Ohoud Aljuhani, Ghazwa B Korayem, Ali F Altebainawi, Raghdah S Alenezi, Shmeylan Al Harbi, Jawaher Gramish, Raed Kensara, Awattif Hafidh, Huda Al Enazi, Ahad Alawad, Rand Alotaibi, Abdulaziz Alshehri, Omar Alhuthaili, Ramesh Vishwakarma, Khalid Bin Saleh, Thamer Alsulaiman, Rahaf Ali Alqahtani, Sajid Hussain, Saja Almazrou, Khalid Al Sulaiman
发表日期
2022/9
期刊
Journal of Intensive Care Medicine
卷号
37
期号
9
页码范围
1238-1249
出版商
SAGE Publications
简介
Background
Aspirin is widely used as a cardioprotective agent due to its antiplatelet and anti-inflammatory properties. The literature has assessed and evaluated its role in hospitalized COVID-19 patients. However, no data are available regarding its role in COVID-19 critically ill patients. This study aimed to evaluate the use of low-dose aspirin (81-100 mg) and its impact on outcomes in critically ill patients with COVID-19.
Method
A multicenter, retrospective cohort study of all critically ill adult patients with confirmed COVID-19 admitted to intensive care units (ICUs) between March 1, 2020, and March 31, 2021. Eligible patients were classified into two groups based on aspirin use during ICU stay. The primary outcome was in-hospital mortality, and other outcomes were considered secondary. Propensity score matching was used (1:1 ratio) based on the selected criteria.
Results
A total of 1033 patients were eligible, and …
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AF Al Harthi, O Aljuhani, GB Korayem, AF Altebainawi… - Journal of Intensive Care Medicine, 2022