作者
Frederik Dalgaard, Jannik L Pallisgaard, Anna‐Karin Numé, Tommi Bo Lindhardt, Gunnar H Gislason, Christian Torp‐Pedersen, Martin H Ruwald
发表日期
2019/10
期刊
Journal of the American Geriatrics Society
卷号
67
期号
10
页码范围
2023-2030
出版商
John Wiley & Sons, Inc.
简介
OBJECTIVES
Management of atrial fibrillation (AF) with rate and/or rhythm control could lead to fall‐related injuries and syncope, especially in the older AF population. We aimed to determine the association of rate and/or rhythm control with fall‐related injuries and syncope in a real‐world older AF cohort.
DESIGN
A retrospective cohort study.
SETTING
Danish nationwide administrative registries from 2000 to 2015.
PARTICIPANTS
A total of 100 935 patients with AF aged 65 years or older claiming prescription of rate‐lowering drugs (RLDs) and/or anti‐arrhythmic drugs (AADs) were included. We compared the use of rate‐lowering monotherapy with rate‐lowering dual therapy, AAD monotherapy, and AAD combined with rate‐lowering therapy.
MEASUREMENTS
Outcomes were fall‐related injuries and syncope as a composite end point (primary) or separate end point (secondary).
RESULTS
In this …
引用总数
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