作者
Thomas E Southard, Karin A Southard, Kenneth E Krizan, Stephen L Hillis, John W Haller, John Keller, Michael W Vannier
发表日期
2000/2/1
期刊
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
卷号
89
期号
2
页码范围
244-249
出版商
Mosby
简介
Objective
Our goal in this investigation was to examine the mandibular bone density and radiographic textural changes and the relationship between mandibular and spinal bone mineral density in an osteoporotic rabbit model.
Study design
Three adult female New Zealand white rabbits in each of 4 groups received daily injections of cortisone acetate at a dosage of 0.0 (control), 3.0, 7.5, or 15.0 mg/kg for 4 weeks. The rabbits were then killed, and the mandible and spine of each animal were removed. Digital radiographs (70 kVp, 10 mA, 8 impulses) of the hemimandibles and spines were made. Lateral and anteroposterior bone densities of the lumbar spine (L2) were calculated, and average mandibular interdental bone density, fractal dimension, and gradient values were calculated.
Results
Correlation analysis revealed that cumulative steroid dose was strongly related to mandibular bone density (r = –0.80, P < …
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TE Southard, KA Southard, KE Krizan, SL Hillis… - Oral Surgery, Oral Medicine, Oral Pathology, Oral …, 2000