查看文章

Introduction. Carbapenem‐resistant Acinetobacter baumannii has been responsible for an increasing number of hospital‐acquired infections globally. The study investigated the prevalence of carbapenemase‐encoding genes in clinical multidrug‐resistant A. baumannii strains. Materials and Methods. A total of 100 nonduplicate multidrug‐resistant A. baumannii strains were cultured from clinical samples obtained from healthcare facilities in the O. R. Tambo district. The strains were confirmed by detecting the intrinsic bla_OXA-51-like gene. Antimicrobial susceptibility testing was performed by VITEK^® 2 and autoSCAN‐4 systems. The MIC of imipenem and meropenem was rechecked by E‐test. Colistin MIC was confirmed by the broth microdilution method. Real‐time PCR was performed to investigate the presence of carbapenemase‐encoding genes. Results. Most strains showed high resistance rates (>80%) to the …