作者
Kurt Spiteri Cornish, Noemi Lois, Neil W Scott, Jennifer Burr, Jonathan Cook, Charles Boachie, Ramin Tadayoni, Morten la Cour, Ulrik Christensen, Alvin KH Kwok
发表日期
2014/3/1
来源
Ophthalmology
卷号
121
期号
3
页码范围
649-655
出版商
Elsevier
简介
Objective
To determine whether internal limiting membrane (ILM) peeling improves anatomic and functional outcomes of full-thickness macular hole (FTMH) surgery when compared with the no-peeling technique.
Design
Systematic review and individual participant data (IPD) meta-analysis undertaken under the auspices of the Cochrane Eyes and Vision Group. Only randomized controlled trials (RCTs) were included.
Participants and Controls
Patients with idiopathic stage 2, 3, and 4 FTMH undergoing vitrectomy with or without ILM peeling.
Intervention
Macular hole surgery, including vitrectomy and gas endotamponade with or without ILM peeling.
Main Outcome Measures
Primary outcome was best-corrected distance visual acuity (BCdVA) at 6 months postoperatively. Secondary outcomes were BCdVA at 3 and 12 months; best-corrected near visual acuity (BCnVA) at 3, 6, and 12 months; primary (after a single …
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