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To determine whether there are notable disparities between popular (Internet) and scientific (Index Medicus) theories of carpal tunnel syndrome (CTS) causation.

Reports from 3 sources were evaluated with regard to support for etiological theories of CTS: 1) patient-oriented information on CTS from the Internet, 2) recent physician-oriented information on CTS from medical journals indexed on Index Medicus, and 3) articles addressing the etiology of CTS from the 1997 National Institute for Occupational Safety and Health report. Multiple logistic regression analyses evaluated differences in etiological theories from the 3 sources.

Internet sites implicated vitamin B₆ deficiency, tenosynovitis, and typing or computer use as causes for idiopathic CTS considerably more often and genetic predisposition considerably less often than recent Index Medicus scientific reports and reports …