作者
Tithi Biswas, Paul Okunieff, Michael C Schell, Therese Smudzin, Webster H Pilcher, Robert S Bakos, G Edward Vates, Kevin A Walter, Andrew Wensel, David N Korones, Michael T Milano
发表日期
2009/12
期刊
Radiation Oncology
卷号
4
页码范围
1-9
出版商
BioMed Central
简介
Purpose
This retrospective study was done to better understand the conditions for which stereotactic radiosurgery (SRS) for glioblastoma may be efficacious.
Methods
Between 2000 and 2007, 33 patients with a pathological diagnosis of glioblastoma received SRS with the Novalis® Shaped Beam Radiosurgery system. Eighteen patients (54%) underwent salvage SRS for recurrence while 15 (45%) patients received upfront SRS following standard fractionated RT for newly diagnosed glioblastoma.
Results
There were no RTOG grade >2 acute side effects. The median survival after SRS was 6.7 months (range 1.4 – 74.7). There was no significant difference in overall survival (from the time of initial diagnosis) with respect to the timing of SRS (p = 0.2). There was significantly better progression free survival in patients …
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