作者
Lise J Estcourt, Claudia S Cohn, Monica B Pagano, Claire Iannizzi, Nina Kreuzberger, Nicole Skoetz, Elizabeth S Allen, Evan M Bloch, Gregory Beaudoin, Arturo Casadevall, Dana V Devine, Farid Foroutan, Thomas J Gniadek, Ruchika Goel, Jed Gorlin, Brenda J Grossman, Michael J Joyner, Ryan A Metcalf, Jay S Raval, Todd W Rice, Beth H Shaz, Ralph R Vassallo, Jeffrey L Winters, Aaron AR Tobian
发表日期
2022/9
期刊
Annals of internal medicine
卷号
175
期号
9
页码范围
1310-1321
出版商
American College of Physicians
简介
Description
Coronavirus disease 2019 convalescent plasma (CCP) has emerged as a potential treatment of COVID-19. However, meta-analysis data and recommendations are limited. The Association for the Advancement of Blood and Biotherapies (AABB) developed clinical practice guidelines for the appropriate use of CCP.
Methods
These guidelines are based on 2 living systematic reviews of randomized controlled trials (RCTs) evaluating CCP from 1 January 2019 to 26 January 2022. There were 33 RCTs assessing 21 916 participants. The results were summarized using the GRADE (Grading of Recommendations Assessment, Development and Evaluation) method. An expert panel reviewed the data using the GRADE framework to formulate recommendations.
Recommendation 1 (Outpatient)
The AABB suggests CCP transfusion …
引用总数