作者
Xiangyu Wang, Yihang Qi, Xiangyi Kong, Jie Zhai, Yalun Li, Yan Song, Jing Wang, Xiaoli Feng, Yi Fang
发表日期
2019/2/1
来源
Cancer letters
卷号
442
页码范围
409-428
出版商
Elsevier
简介
Triple-negative breast cancer (TNBC) refers to cancers that are low in expression of the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). TNBC tends to behave more aggressively than other types of breast cancer. Unlike other breast cancer subtypes (ie, ER-positive, HER2-positive subtypes), there are no approved targeted treatments available, other than the administration of chemotherapy. Immunotherapy is a new kind of treatment approach for TNBC when compared with the surgical treatment, chemotherapy, endocrine therapy, and molecular targeting therapy. The present article reviews the research progresses of immunotherapy for TNBC in recent years. The full text structure covers molecular classification of TNBC, active immunotherapy of TNBC, passive immunotherapy of TNBC, oncolytic immunotherapy and the prospect of immunotherapy for TNBC.
引用总数
201820192020202120222023202417714863
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