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To investigate the effects of postoperative intensive glycemic control on patient outcomes.

Ineffective perioperative glycemic control has been associated with high mortality and morbidity rates among cardiac surgery patients.

212 cardiac surgery patients were allocated by a quasi-experimental design to: a) a control group (n = 107) with targeted blood glucose levels 161–200 mg/dl or b) a therapy group (n = 105) with blood glucose target 120–160 mg/dl. We compared the two groups on their mortality, length of stay, duration of intubation, incidence of severe hypoglycemia and frequency of postoperative infections.

The mean postoperative blood glucose levels were significantly lower for the therapy group compared with the control group (153.9 mg/dl vs. 173.9 md/dl, p < 0.001). The intensive glycemic control was strongly associated with decreased in-hospital …