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With immense sadness, we write and honor Gian Maria who passed away in Rome aged only 56 years. Gian Maria (Giamma to his close friends) was a dear friend and an inspiration for his generation, not simply because of his professional achievements, but equally for his warm personality, exemplary hard playing life, and unbounded enthusiasm. His premature death, on January 22, 2024, following a tragic unexpected and extremely rapid illness, has left all his family and friends speechless. Giamma started his career in 1992 at the University of Rome “La Sapienza” with a PhD under the guidance of Professor Paolo Amati. Following his Post-doc training at the Institute of Genetics, Molecular and Cellular Biology (IGBMC) in Strasbourg, France, in the laboratory of Prof. Paolo Sassone-Corsi (1996–2000), he then joined, in the year 2000, the Laboratory of Cellular Biology and Electron Microscopy at the National …