作者
Tracy M Flanders, Shih-Shan Lang, Tiffany S Ko, Kristen N Andersen, Jharna Jahnavi, John J Flibotte, Daniel J Licht, Gregory E Tasian, Susan T Sotardi, Arjun G Yodh, Jennifer M Lynch, Benjamin C Kennedy, Phillip B Storm, Brian R White, Gregory G Heuer, Wesley B Baker
发表日期
2021/9/1
期刊
The Journal of pediatrics
卷号
236
页码范围
54-61. e1
出版商
Mosby
简介
Objective
To demonstrate that a novel noninvasive index of intracranial pressure (ICP) derived from diffuse optics-based techniques is associated with intracranial hypertension.
Study design
We compared noninvasive and invasive ICP measurements in infants with hydrocephalus. Infants born term and preterm were eligible for inclusion if clinically determined to require cerebrospinal fluid (CSF) diversion. Ventricular size was assessed preoperatively via ultrasound measurement of the fronto-occipital (FOR) and frontotemporal (FTHR) horn ratios. Invasive ICP was obtained at the time of surgical intervention with a manometer. Intracranial hypertension was defined as invasive ICP ≥15 mmHg. Diffuse optical measurements of cerebral perfusion, oxygen extraction, and noninvasive ICP were performed preoperatively, intraoperatively, and postoperatively. Optical and ultrasound measures were compared with invasive …
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TM Flanders, SS Lang, TS Ko, KN Andersen, J Jahnavi… - The Journal of pediatrics, 2021