作者
Martin Voss, James Moore, Marta Hauser, Juergen Gallinat, Andreas Heinz, Patrick Haggard
发表日期
2010/10/1
期刊
Brain
卷号
133
期号
10
页码范围
3104-3112
出版商
Oxford University Press
简介
Patients suffering from schizophrenia may report unusual experiences of their own actions. They may either feel that external forces are controlling their actions or even their thoughts, or they may feel in control of events that in fact are not caused by their actions. Most theories link these disturbances in the sense of agency to deficits in motor prediction, resulting in a mismatch between predicted and actual sensory feedback at a central comparator mechanism. Such theories therefore can account for situations in which the sense of agency is reduced. However, other experiments as well as clinical observations show an enhanced rather than reduced sense of agency in schizophrenic patients. Here, we distinguish between a predictive and a retrospective mechanism where both contribute to the experience of agency, and show that schizophrenia is associated with a specific impairment to the predictive …
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