作者
Marc Brisson, Jane J Kim, Karen Canfell, Mélanie Drolet, Guillaume Gingras, Emily A Burger, Dave Martin, Kate T Simms, Élodie Bénard, Marie-Claude Boily, Stephen Sy, Catherine Regan, Adam Keane, Michael Caruana, Diep TN Nguyen, Megan A Smith, Jean-François Laprise, Mark Jit, Michel Alary, Freddie Bray, Elena Fidarova, Fayad Elsheikh, Paul JN Bloem, Nathalie Broutet, Raymond Hutubessy
发表日期
2020/2/22
期刊
The Lancet
卷号
395
期号
10224
页码范围
575-590
出版商
Elsevier
简介
Background
The WHO Director-General has issued a call for action to eliminate cervical cancer as a public health problem. To help inform global efforts, we modelled potential human papillomavirus (HPV) vaccination and cervical screening scenarios in low-income and lower-middle-income countries (LMICs) to examine the feasibility and timing of elimination at different thresholds, and to estimate the number of cervical cancer cases averted on the path to elimination.
Methods
The WHO Cervical Cancer Elimination Modelling Consortium (CCEMC), which consists of three independent transmission-dynamic models identified by WHO according to predefined criteria, projected reductions in cervical cancer incidence over time in 78 LMICs for three standardised base-case scenarios: girls-only vaccination; girls-only vaccination and once-lifetime screening; and girls-only vaccination and twice-lifetime screening. Girls …
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