作者
Paul C Donaghy, Nicola Barnett, Kirsty Olsen, John‐Paul Taylor, Ian G McKeith, John T O'Brien, Alan J Thomas
发表日期
2017/11
期刊
International Journal of Geriatric Psychiatry
卷号
32
期号
11
页码范围
1163-1171
简介
Objective
Dementia with Lewy bodies (DLB) is associated with a range of cognitive and non‐cognitive symptoms. We aimed to identify if some of these symptoms might aid early diagnosis of Lewy body disease in cases of mild cognitive impairment (MCI).
Methods
Lewy body MCI (MCI‐LB; n = 36), Alzheimer's disease MCI (MCI‐AD; n = 21), DLB (n = 36), AD (n = 21) and control (n = 20) participants were recruited. An interview‐based questionnaire about the presence of symptoms thought to be associated with Lewy body disease was completed by participants with, where possible, their carer/relative. The prevalence of each symptom was compared between MCI‐LB and MCI‐AD and between established DLB and AD, and a symptom scale based on these findings was devised.
Results
Fluctuating concentration/attention; episodes of confusion; muscle rigidity; changes in hand‐writing, gait and posture; falls …
引用总数
20182019202020212022202320244799689
学术搜索中的文章
PC Donaghy, N Barnett, K Olsen, JP Taylor, IG McKeith… - International Journal of Geriatric Psychiatry, 2017