作者
Idan Steinberg, Nir Turko, Omri Levi, Israel Gannot, Avishay Eyal
发表日期
2016/9
期刊
Journal of biophotonics
卷号
9
期号
9
页码范围
924-933
出版商
WILEY‐VCH Verlag
简介
Osteoporosis is a major public health problem worldwide. Here, we present a quantitative multispectral photoacoustic method for the evaluation of bone pathologies which has significant advantages over pure ultrasonic or pure optical methods as it provides both molecular information and bone mechanical status. This is enabled via a simultaneous measurement of the bone's optical properties as well as the speed of sound and ultrasonic attenuation in the bone. To test the method's quantitative predictions, a combined ultrasonic and photoacoustic system was developed. Excitation was performed optically via a portable triple laser‐diode system and acoustically via a single element transducer. Additional dual transducers were used for detecting the acoustic waves that were generated by the two modalities. Both temporal and spectral parameters were compared between different excitation wavelengths and …
引用总数
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