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Interstitial lung abnormalities (ILA) are incidental findings on chest computed tomography (CT) that may represent an early-stage of pulmonary fibrosis (PF). It is unknown if prevalence or severity of ILA differ among racial groups. COPDGene is a longitudinal multicenter cohort of smokers, self-identified as non-Hispanic White (NHW) or Black/African American (B/AA). The analytic cohort included participants with visually assessed ILA (n= 529 phase 1; 586 phase 2). Sequential multivariable linear regression models were used to determine the association between race and measures of severity (FVC, 6MWD, age at death (AAD); accounting for the independent influence of various factors (demographic, environmental, social drivers of health (SDOH, education, income, insurance status), and principal components of ancestry. Adjusted R2 compared global explanatory power of the models. F-tests …