作者
Irene L Katzan, Maxim D Hammer, Eric D Hixson, Anthony J Furlan, Alex Abou-Chebl, Deborah M Nadzam
发表日期
2004/3/1
期刊
Archives of neurology
卷号
61
期号
3
页码范围
346-350
出版商
American Medical Association
简介
Background
Intravenous tissue plasminogen activator (tPA) is the only approved therapy for acute ischemic stroke, although only 2% of patients with stroke receive intravenous tPA nationally.
Objective
To determine the rate of tPA use for stroke in the Cleveland, Ohio, community and the reasons why patients were excluded from thrombolysis treatment.
Design
Retrospective cohort study.
Setting
Community.
Subjects
Patients admitted because of stroke to the 9 Cleveland Clinic Health System hospitals from June 15, 1999, to June 15, 2000.
Main Outcome Measures
Utilization of intravenous tPA and reasons for ineligibility.
Results
There were 1923 admissions for ischemic stroke in the 1-year period. Of these, 288 (15.0%) arrived within the 3-hour time window, and approximately 6.9% were considered eligible for tPA. The most common reasons for exclusion among patients arriving within 3 hours were mild neurologic …
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