作者
Raghava S Velagaleti, Michael J Pencina, Joanne M Murabito, Thomas J Wang, Nisha I Parikh, Ralph B D'Agostino, Daniel Levy, William B Kannel, Ramachandran S Vasan
发表日期
2008/11/11
期刊
Circulation
卷号
118
期号
20
页码范围
2057-2062
出版商
Lippincott Williams & Wilkins
简介
Background— Although mortality after myocardial infarction (MI) has declined in the United States in recent decades, there have been few community-based investigations of the long-term trends in the incidence of heart failure after MI, and their results appear to be conflicting.
Methods and Results— We evaluated 676 Framingham Heart Study participants between 45 and 85 years of age (mean age 67 years, 34% women) who developed a first MI between 1970 and 1999. We assessed the incidence rates of heart failure and of death without heart failure in each of 3 decades (1970 to 1979, 1980 to 1989, and 1990 to 1999). We estimated the multivariable-adjusted risk of events in the latter 2 decades, with the period 1970 to 1979 serving as the referent. The 30-day incidence of heart failure after MI rose from 10% in 1970 to 1979 to 23.1% in 1990 to 1999 (P for trend 0.003), whereas 30-day mortality after MI …
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