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Twitter offers a potentially novel investigation line to evaluate self-perception and awareness in the context of the public health response to the coronavirus disease (COVID-19) pandemic. Studies have shown that Twitter content may provide crucial insights into the ongoing public health crisis. 1, 2 However, some studies suggest that Twitter may play an important role in propagating misinformation in previous epidemics such as the Zika, Ebola, and yellow fever virus outbreaks. 3-5 In the COVID-19 era, scientists and clinicians use Twitter to echo scientific evidence, especially toward an academic audience. However, in nonacademic contexts, the effect of Twitter in the COVID-19 era on public perception, whether beneficial or harmful, remains unknown. We hypothesize that there may be significant variation in signals of Twitter related to COVID-19 in nonacademic contexts.

We extracted all Tweets and hashtags …