作者
Charat Thongprayoon, Ploypin Lertjitbanjong, Wisit Cheungpasitporn, Panupong Hansrivijit, Tibor Fülöp, Karthik Kovvuru, Swetha R Kanduri, Paul W Davis, Saraschandra Vallabhajosyula, Tarun Bathini, Kanramon Watthanasuntorn, Narut Prasitlumkum, Ronpichai Chokesuwattanaskul, Supawat Ratanapo, Michael A Mao, Kianoush Kashani
发表日期
2020/1/1
期刊
Renal Failure
卷号
42
期号
1
页码范围
495-512
出版商
Taylor & Francis
简介
Background
We aimed to evaluate the acute kidney injury (AKI) incidence and its associated risk of mortality in patients with implantable left ventricular assist devices (LVAD).
Methods
A systematic literature search in Ovid MEDLINE, EMBASE, and Cochrane Databases was conducted through January 2020 to identify studies that provided data on the AKI incidence and AKI-associated mortality risk in adult patients with implantable LVADs. Pooled effect estimates were examined using random-effects, generic inverse variance method of DerSimonian-Laird.
Results
Fifty-six cohort studies with 63,663 LVAD patients were enrolled in this meta-analysis. The pooled incidence of reported AKI was 24.9% (95%CI: 20.1%–30.4%) but rose to 36.9% (95%CI: 31.1%–43.1%) when applying the standard definition of AKI per RIFLE, AKIN, and KDIGO criteria. The pooled incidence of severe AKI requiring renal replacement therapy …
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C Thongprayoon, P Lertjitbanjong, W Cheungpasitporn… - Renal Failure, 2020