作者
Michail Alevizakos, Dimitrios Nasioudis, Eleftherios Mylonakis
发表日期
2017/12
来源
Transplant Infectious Disease
卷号
19
期号
6
页码范围
e12759
简介
Background
Urinary tract infections (UTIs) are the most common infectious complications among renal transplant recipients (RTR). UTIs caused by extended‐spectrum beta‐lactamase (ESBL)‐producing Enterobacteriaceae (ESBL‐PE) have been associated with inferior clinical outcomes and increased financial burden.
Methods
We performed a systematic review and meta‐analysis by searching through the PubMed and EMBASE databases (to May 20, 2016) and identifying studies that reported data on the number of RTR who developed an ESBL‐PE UTI.
Results
Our analysis included seven studies, out of 357 non‐duplicate articles, that provided data on 2824 patients. Among them, 10% (95% confidence interval [CI] 4%‐17%) developed an ESBL‐PE UTI over their follow‐up periods. The proportion of RTR affected by an ESBL‐PE UTI was 2% in North America (95% CI 1%‐3%), 5% in Europe (95% CI 4%‐6 …
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