作者
Dionysios Neofytos, Olga Chatzis, Dimitrios Nasioudis, Elsa Boely Janke, Thanh Doco Lecompte, Christian Garzoni, Christoph Berger, A Cussini, Katia Boggian, Nina Khanna, Oriol Manuel, Nicolas J Mueller, Christian van Delden, Swiss Transplant Cohort Study, Patrizia Amico, John‐David Aubert, Vanessa Banz, Guido Beldi, Christian Benden, Isabelle Binet, Pierre‐Yves Bochud, Elsa Boëly, Heiner Bucher, Thierry Carell, Emmanuelle Catana, Yves Chalandon, Sabina de Geest, Olivier de Rougemont, Michael Dickenmann, Michel Duchosal, Laure Elkrief, Thomas Fehr, Sylvie Ferrari‐Lacraz, Paola Gasche Soccal, Paola Gasche Soccal, Christophe Gaudet, Emiliano Giostra, Déla Golshayan, Karine Hadaya, Jörg Halter, Dominik Heim, Christoph Hess, Sven Hillinger, Hans H Hirsch, Günther Hofbauer, Uyen Huynh‐Do, Franz Immer, Richard Klaghofer, Michael Koller, Bettina Laesser, Roger Lehmann, Christian Lovis, Pietro Majno, Hans‐Peter Marti, Pierre Yves Martin, Pascal Meylan, Paul Mohacsi, Philippe Morel, Ulrike Mueller, Helen Mueller‐McKenna, Antonia Müller, Thomas Müller, Beat Müllhaupt, Manuel Pascual, Jakob Passweg, Klara Posfay‐Barbe, Juliane Rick, Eddy Roosnek, Anne Rosselet, Silvia Rothlin, Frank Ruschitzka, Urs Schanz, Stefan Schaub, Aurelia Schnyder, Christian Seiler, Jan Sprachta, Susanne Stampf, Jürg Steiger, Guido Stirnimann, Christian Toso, Jean‐Pierre Venetz, Jean Villard, Madeleine Wick, Markus Wilhelm, Patrick Yerly
发表日期
2018/8
期刊
Transplant infectious disease
卷号
20
期号
4
页码范围
e12898
简介
Background
There is lack of recent multicenter epidemiological data on invasive aspergillosis (IA) among solid organ transplant recipient (SOTr) in the mold‐acting antifungal era. We describe the epidemiology and outcomes of IA in a contemporary cohort of SOTr using the Swiss Transplant Cohort Study.
Methods
All consecutive SOTr with proven or probable IA between 01.05.2008 and 31.12.2014 were included. A case‐control study to identify IA predictors was performed: 1‐case was matched with 3‐controls based on SOT type, transplant center, and time post‐SOT.
Results
Among 2868 SOTr, 70 (2.4%) patients were diagnosed with proven (N: 30/70, 42.9%) or probable (N: 40/70, 57.1%) IA. The incidence of IA was 8.3%, 7.1%, 2.6%, 1.3%, and 1.2% in lung, heart, combined, kidney, and liver transplant recipients, respectively, Galactomannan immunoassay was positive in 1/3 of patients tested. Only 33/63 …
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D Neofytos, O Chatzis, D Nasioudis, E Boely Janke… - Transplant infectious disease, 2018